Running Django on [[http://pypy.org/ | PyPy]] boils down to installing both and running Django with `pypy` instead of `python`.

Download a [[http://pypy.org/ | PyPy]] binary from http://pypy.org/download.html and follow the install instructions there.

Run Django the usual way with [[http://pypy.org/ | PyPy]]:
{{{
pypy ./manage.py syncdb
pypy ./manage.py runserver
}}}

[[http://pypy.org/ | PyPy]]
[[http://speed.pypy.org/timeline/?ben=django|runs the templating engine faster]]
than CPython, but so far DB access is slower for some drivers.

Some C-based DB drivers don't work with [[http://pypy.org/ | PyPy]]. See the
[[https://bitbucket.org/pypy/compatibility/wiki/Home#!db-adaptors | Compatibility Wiki]] for an overview of what works.